Tag: unemployment

TL;DR

• US job openings jumped to roughly 7.6 million in May 2026 on the BLS JOLTS report, beating forecasts from outlets like CNN and AP and putting the headline labor market back in the spotlight—but it’s a paper tiger if companies still aren’t actually hiring at scale. [1][2][3]
• The power metric isn’t openings; it’s quits. With the quits rate stuck at 1.9% and the Conference Board showing 22.5% of consumers say jobs are “hard to get,” workers aren’t acting like they have bargaining power, which blunts wage-and-inflation fears. [2][6]
• Sector splits matter: construction, manufacturing, and leisure/hospitality raised postings, while finance and information tightened belts—telling CFOs in 2026 to budget for blue-collar scarcity but white-collar slack. [2]

What the source said

CNN reports that US job openings were “much higher than expected” in May 2026, with the JOLTS tally rising for a second straight month to nearly 7.6 million. Economists had anticipated a decline closer to ~7.0 million, but openings instead hovered near a two‑year high. CNN frames the result as evidence the labor market has stabilized despite uncertainty from the Iran war, while also noting layoffs and quits changed little; the layoffs and discharges rate held near 1.0%. The piece highlights differing momentum across industries and argues the “hiring recession” may be ending—albeit tentatively. [1][2]

Why it matters

For the Federal Reserve in Washington, US job openings are a headline indicator that often overstates heat. Monetary policy cares about wages and churn—metrics like a 1.9% quits rate and “modest” wage growth from the Beige Book that actually push prices. A high openings count with flat hires near ~5.2 million and low quits is the definition of “low‑hire, low‑fire,” which pressures neither wages nor inflation. That tilts the 2026 policy debate away from emergency tightening and toward watching three‑to‑six‑month trends. [2][5]

For companies and workers, the distribution is the story. A construction firm in Dallas will feel a tighter market than a fintech in New York. May 2026 JOLTS showed blue‑collar strength (construction, manufacturing, parts of trade) and white‑collar caution (finance, information). That mix determines where signing bonuses return, where ghost postings persist, and who wins the next wage negotiation this year. [2]

Original analysis

Back-of-envelope math

• Openings-to-unemployed ratio. Openings were 7.594 million in May 2026; the number of unemployed people was about 7.3 million. That pegs the ratio near 1.04 (7.594 ÷ 7.3 ≈ 1.04). Translation: roughly one posted job per job seeker, down from the 1.5–2.0 range at the 2022 peak, but still tighter than 2019’s near‑parity. [2][7][8]

• The conversion gap. Hires were about 5.18 million in May versus 7.594 million openings, a gap of ~2.41 million postings that did not convert during the month. This isn’t apples‑to‑apples (openings are a stock; hires are a flow), but the gap’s scale helps explain why the quits rate can sit at 1.9% even when openings look lofty. [2][3]

• If quits normalize. The pre‑pandemic quits rate hovered near 2.3% in 2019; today it’s 1.9%. The delta is 0.4 percentage points (0.023 − 0.019 = 0.004). On a workforce around 160 million, that implies roughly 640,000 additional quits per month if quits returned to the 2019 norm (0.004 × 160,000,000 ≈ 640,000)—material churn that would lift wage pressure; we’re not there. [2][7][8]

A 2×2 for US job openings and hires momentum (May 2026)

• Rising openings, rising hires (early‑cycle feel)

  • Leisure & hospitality: openings +95k (846k → 941k); hires +15k (976k → 991k). Summer travel demand and services spending support this pulse. [2]
  • Government (state/local): openings +20k (697k → 717k); hires +21k (302k → 323k). Local services normalized post‑pandemic staffing. [2]

• Rising openings, falling hires (bottlenecks or cautious conversion)

  • Wholesale trade: openings +71k (178k → 249k); hires −20k (141k → 121k). Inventory restocking wants heads, but managers aren’t pulling triggers yet. [2]

• Falling openings, rising or flat hires (drawdown of backlog)

  • Education & health: openings −119k (1,658k → 1,539k); hires +1k (737k → 738k). Health‑care pipelines keep clearing even as postings cool. [2]
  • Information: openings −6k (82k → 76k); hires +2k (78k → 80k) is basically flat—still post‑AI digestion mode in 2026. [2]

• Falling openings, falling hires (real softening)

  • Financial activities: openings −29k (405k → 376k); hires −7k (181k → 174k). Margin compression and credit risk discipline curb reqs and fills. [2]

Consensus says “openings beat = tight labor market.” Contrarian read: this is a reposting economy, not a rehiring economy. Hires are stuck near 5.2 million, quits are stuck at 1.9%, and the Fed’s Beige Book keeps calling wage growth “modest.” That triad isn’t inflationary; it’s stasis. [2][5]

What about sentiment? The Conference Board’s June 2026 survey shows the share saying “jobs are hard to get” jumped to 22.5%, the highest since January 2021. If households feel jobs are scarcer, they don’t quit—and if they don’t quit, wage bargaining power stalls. That squares with JOLTS’ 1.9% quits rate and ~5.2 million hires. [2][6]

Geopolitics is the wrinkle. Beige Book districts in 2026 flagged price pressures tied to the Middle East conflict and energy costs, but employment described as “flat to unchanged.” In other words: the war can tax the price level without reigniting labor churn. That’s why the May openings pop coexists with modest wages and still‑constrained hiring. [5]

Named-stakeholder snapshot

• Federal Reserve: Headline openings buy time but don’t force hikes in 2026. With hires flat near ~5.2 million and quits subdued at 1.9%, wage‑push inflation risk looks contained; the Committee will emphasize trend, not a single data point. [2][5]

• Blue‑collar employers (D.R. Horton, Caterpillar, Marriott): Brace for tighter local markets as construction, manufacturing, and leisure openings climb in May 2026. Expect spot bonuses and overtime before full‑time net adds. [2]

• White‑collar employers (JPMorgan, Salesforce, Comcast): Finance and information show cautious demand; use mid‑2026 to upgrade talent quality without overpaying, but avoid ghost postings that damage brand trust. [2]

• Staffing firms (Robert Half, Adecco): Wholesale trade’s “rising reqs, falling hires” calls for tighter conversion playbooks and clearer comp‑to‑fill timelines in Q3 2026. [2]

What others are missing

Coverage is underweight the “jobs hard to get” surge and what it says about matching quality and trust in 2026. In June, the Conference Board’s share of consumers saying jobs are “hard to get” jumped to 22.5%, a 5½‑year high, even as May JOLTS openings sat at 7.594 million. The specific angle: phantom postings and evergreen reqs create a credibility gap that suppresses quits, which explains why the quits rate stays at 1.9% and why the Beige Book shows “modest” wage growth despite fat postings. If candidates doubt a posting is real or worth the risk, they won’t move; if managers keep reqs evergreen to gauge talent, they won’t convert. That’s why inflation hawks shouldn’t overreact to a single openings print in May 2026. [2][5][6]

What to watch next

1. By the June 2026 JOLTS release expected in early August 2026, the openings‑to‑unemployed ratio will remain between 0.95 and 1.10, confirming a balanced, not boiling, market. [2][7]

2. Through the September 2026 JOLTS (due November 2026), the quits rate will stay at or below 2.0%, keeping wage growth near its current “modest” pace rather than re‑accelerating. [2][5]

3. By the July 2026 JOLTS (due September 2026), wholesale trade openings will retrace from 249k to below 220k, revealing the May spike as inventory noise rather than sustained demand. [2]

My take

Openings got the headline, but hires and quits got the truth: ~5.2 million hires and a 1.9% quits rate in May 2026. This is a stalemate labor market where employers prefer to post and wait rather than hire and train, and workers prefer to stay put rather than jump and risk. That’s not the setup for a wage spiral or a sudden growth bust in 2026. It’s the setup for grind—modest pay gains, selective scarcity, and a lot of “we’re keeping the req open” emails. If you run a business, budget for targeted blue‑collar shortages and white‑collar abundance; if you run the Fed, keep your powder dry and watch churn, not chatter. [2][5][6]

Sources

1. US job openings were much higher than expected in May, shrugging off uncertainty from Iran war — CNN (https://www.cnn.com/2026/06/30/economy/us-jolts-job-openings-layoffs-may) — Starting point: topline JOLTS beat, two‑year‑high framing, and context around uncertainty.

2. Job Openings and Labor Turnover Survey (Latest numbers and May 2026 news release) — U.S. Bureau of Labor Statistics (https://www.bls.gov/jlt/) — Authoritative figures for May 2026: openings 7.594M, hires ~5.2M, separations ~5.1M, quits rate 1.9%; plus industry tables.

3. Job openings stayed at a surprisingly strong 7.6 million in May; U.S. labor market proves resilient — Associated Press (https://apnews.com/article/2947b00cdf3fadacf28c50ad508a6502) — Independent confirmation that openings beat forecasts while hiring remained subdued.

4. May 2026 JOLTS Report: More of the Same — Indeed Hiring Lab (https://www.hiringlab.org/2026/06/30/may-2026-jolts-report-more-of-the-same/) — Analyst take on low quits, flat dynamism, and why postings don’t equal real opportunities.

5. Beige Book (May/June 2026 summaries) — Board of Governors of the Federal Reserve System (https://www.federalreserve.gov/monetarypolicy/beigebook202605-summary.htm) — Fed’s national read: employment largely unchanged and wage growth “modest” amid elevated energy costs.

6. US Consumer Confidence Inched Up in June — The Conference Board (https://www.conference-board.org/topics/consumer-confidence/index.cfm) — “Jobs hard to get” share rose to 22.5% in June 2026, the highest since January 2021.

7. The Employment Situation — May 2026 — U.S. Bureau of Labor Statistics (https://www.bls.gov/news.release/archives/empsit_06052026.pdf) — Unemployment rate at 4.3% with about 7.3 million unemployed; provides the denominator for openings‑to‑unemployed.

8. Job openings, hires, and quits set record highs in 2019 — Monthly Labor Review (BLS) (https://www.bls.gov/opub/mlr/2020/article/job-openings-hires-and-quits-set-record-highs-in-2019.htm) — Background on the 2019 quits norm (~2.3%) for benchmarking 2026’s 1.9% rate.

TL;DR

• A Business Insider story shows a tech worker broke a 10‑month unemployment streak by bringing doughnuts to an office and introducing himself—an old‑school tactic that cut through an application pile and led to a hire. [1]
• In 2024, Workday reported 173 million applications for 19 million requisitions and said applications grew 4× faster than openings; meanwhile, the BLS puts median jobless spells around 11.5 weeks and the mean near 25.3 weeks, making visibility tactics a rational bet. [2][3]
• The move isn’t universally smart: it works where norms allow small, shared treats and walk‑ins; it backfires in regulated or policy‑heavy orgs that bar gifts—even doughnuts. [4][5]

What the source said

Business Insider recounts how a laid‑off tech professional, after months of ghosting, visited a local employer in person with a box of doughnuts and introduced himself at reception. Staff noticed, conversations followed, HR called that day, interviews ensued, and he landed the job. [1]

His spouse—an ex‑recruiter—had doubted the “drop‑in” approach, assuming it was outdated, yet six months later he’d earned a raise and a strong review. The author frames the doughnuts as a symbol of tenacity and a way to force a personal, human interaction in a process dominated by online applications and AI filters. The story’s moral: when the market is unforgiving, personality and presence can reopen closed doors. [1]

Why it matters

• Stakeholders: job seekers in crowded funnels; small and midsize employers drowning in résumés; HR teams managing policy and fairness; and platforms (LinkedIn/Indeed/Workday) that intermediate this dance. Workday says customers processed 173 million applications for 19 million requisitions in H1 2024; applications grew 4× faster than openings, so standing out—not just “applying more”—is the constraint. [3]

• Stakes: money and time. The BLS shows median unemployment at 11.5 weeks and mean at 25.3 weeks in March–April 2026; every week saved is rent, healthcare, and momentum. Employers face non‑executive cost‑per‑hire around $5,475 and screening bottlenecks that add 8–9 days to cycles, which compounds vacancy costs. Moves that ethically surface signal earlier can compress both sides’ costs. [2][5]

Original analysis

Why “bringing doughnuts to an office” works (sometimes)

• Contrarian read

  • Consensus: “Never bring gifts to interviews; it looks unprofessional or like a bribe.” Indeed’s own advice labels gifts inappropriate. [4]
  • Counterpoint: The story’s power isn’t the sugar; it’s forced salience plus reciprocity in a low‑stakes, shared format. In sectors that tolerate drop‑ins (local services, SMBs) and where staff can accept nominal food, a polite, five‑minute hello can move you from inbox commodity to remembered human—especially as HR tech scales screening. [3][4]

• Back‑of‑envelope ROI (candidate)

  • Facts: Mean unemployment duration ≈ 25.3 weeks (Mar–Apr 2026). Median usual weekly earnings Q1 2026 ≈ $1,235. [2][6]
  • If an in‑person visit advances you by 4 weeks (“top of the pile”), that’s ~4 × $1,235 ≈ $4,940 in regained earnings. A $15–$20 box of doughnuts and a morning of time is trivial against that upside; even a one‑week acceleration yields ≈ $1,235. (Assumes eventual offer; the point is expected value, not guarantee.) [2][6]

• Back‑of‑envelope ROI (employer)

  • SHRM’s 2025 benchmarking pegs non‑executive cost‑per‑hire at about $5,475 and says screening/interviewing alone average 8–9 days. Anything that surfaces a plausible, mission‑fit candidate sooner can trim cycle time and interview hours. [5]

• The “Visibility × Norms” 2×2 (use to decide if this tactic is smart)

  • High‑visibility, loose norms (local services, media sales, many SMB offices): A short, courteous drop‑in with a shared treat for the floor can help. Keep it under five minutes and avoid putting anyone on the spot. [5]
  • High‑visibility, strict norms (federal, defense, hospitals, universities with gift caps): Don’t do it. Many orgs treat unsolicited food as a policy issue, and violating policy embarrasses staff and hurts your candidacy. [5]
  • Low‑visibility, loose norms (warehouse, trades depots, retail back‑office): A quick hello can still help but target shift leaders; highlight certifications (e.g., OSHA‑10) and availability rather than pastry. [5]
  • Low‑visibility, strict norms (finance HQs, regulated utilities, pharma labs): Stick to scheduled appointments, portfolio links, and employee‑referred intros. No food, no drop‑ins. [5]

• Historical analogue

  • In 2016, a San Francisco job seeker delivered résumés inside doughnut boxes to roughly 40 companies and scored 10 interviews—a classic “pattern interrupt” during a competitive tech hiring cycle. Workday’s 2024 finding that applications grew 4× faster than openings describes the same macro condition that makes analog contact effective again. [3][7]

• Named‑stakeholder implications

  • Job boards/ATS vendors (LinkedIn, Indeed, Workday): Expect more “offline hacks” as seekers try to escape high‑volume funnels, increasing pressure to surface human signals (work samples, simulations) earlier. [3]
  • SMB employers: Codify front‑desk scripts for walk‑ins and treats: thank candidates, accept or decline per policy, route to a single intake contact, and maintain equity by logging all drop‑ins the same day. [5]
  • Candidates: If you try an in‑person nudge, honor compliance (no gifts where barred), make it about shared break‑room snacks—not person‑specific presents—and always pair it with a tailored résumé and online application number.

What others are missing

Coverage spotlights the charm, not the constraint: selection bandwidth. When Workday sees 173 million applications against 19 million requisitions in H1 2024, recruiters triage for sanity, not optimality. That means path‑dependent attention: who crosses a human’s field of view first. [3]

A respectful, policy‑compliant in‑person touch simply reorders the queue. Meanwhile, SHRM’s data shows screening and interviewing soak 8–9 days; a hallway micro‑audition can collapse a step. The doughnuts aren’t magic—they are a low‑friction attention token that converts a cold start into a warm referral inside the same day, which is why this tactic disproportionately benefits SMBs with thinner processes. [5]

What to watch next

1. By December 31, 2026, at least two Fortune 100 employers will publish or update public recruiting guidelines that explicitly bar candidate‑provided food or gifts at reception or during interviews.
2. By March 31, 2027, Workday (or a comparable HCM vendor) will report that application growth outpaced job openings year over year in at least half of tracked industries for 2026. [3]
3. By June 30, 2027, at least one major job board (LinkedIn, Indeed, or ZipRecruiter) will pilot or announce a “verified walk‑in” or “office‑hours” feature to standardize equitable, scheduled alternatives to unsanctioned visits. [3][5]

My take

I’m pro‑“polite stunt,” anti‑“policy violation.” In a market that’s more filter than handshake, a small, inclusive gesture that gets you seen—as long as it doesn’t target a specific decision‑maker or breach gift rules—can tilt odds meaningfully. If I were job‑hunting at an SMB in 2026, I’d pair a skills‑first résumé with a five‑minute lobby intro and a box for the whole floor, not the boss. [3][4][5]

In regulated shops, I’d skip the treats and book posted office hours or ship a two‑minute demo video with measurable results (e.g., “cut cycle time 18% on a 2025 pilot”). The principle scales: earn five seconds of genuine attention, ethically. The doughnuts are just one way to buy those five seconds. [5]

Sources

[1] My husband was unemployed for 10 months. He finally landed a job when he turned up at an office with a box of doughnuts. — Business Insider (https://www.businessinsider.com/unemployed-husband-landed-job-unique-trick-2026-5) — The first‑person account that sparked this analysis.

[2] Table A‑12. Unemployed people by duration of unemployment — U.S. Bureau of Labor Statistics (https://www.bls.gov/news.release/empsit.t12.htm) — Confirms mean (25.3 weeks) and median (11.5 weeks) unemployment durations in March–April 2026.

[3] Workday Global Workforce Report press release (Sept. 10, 2024): “Job applications grew four times faster than job openings… 173M applications vs. 19M requisitions (H1 2024)” — Workday Newsroom (https://newsroom.workday.com/2024-09-10-Workday-Global-Workforce-Report-Job-Market-Tightens-as-AI-Reshapes-Hiring-Processes) — Quantifies the application glut that makes offline salience valuable.

[4] 7 Items To Bring to a Job Interview (FAQ: “Is it appropriate to bring a gift to a job interview? It’s inappropriate…”) — Indeed Career Guide (https://www.indeed.com/career-advice/interviewing/what-to-bring-to-a-job-interview) — Represents mainstream guidance against candidate gifts.

[5] SHRM releases 2025 Benchmarking Reports (screening/interviewing average 8–9 days; cost‑per‑hire benchmarks) — Society for Human Resource Management (https://www.shrm.org/about/press-room/shrm-releases-2025-benchmarking-reports–how-does-your-organizat) — Provides time‑to‑stage and cost context employers face.

[6] Median usual weekly earnings of full‑time workers, Q1 2026: $1,235 — U.S. Bureau of Labor Statistics (PDF) (https://www.bls.gov/news.release/pdf/wkyeng.pdf) — Used for back‑of‑envelope candidate ROI.

[7] Man scores 10 interviews by delivering résumé in a box of doughnuts — Good Morning America (https://www.goodmorningamerica.com/news/story/man-scores-10-interviews-resume-delivered-box-doughnuts-42609704) — Historical analogue showing the same “pattern interrupt” worked in 2016.

When fewer men are in the workforce: what's really going on

The share of American men working or searching for a job recently hit the lowest level since 1948, aside from the pandemic — and that sentence makes you pause. It suggests a structural shift, not just a quarterly wobble. Over the last few years, men at both ends of the age spectrum — younger and older — have been stepping out of the labor market in numbers that economists and journalists find striking. This post unpacks the why, the how, and the what-next in a conversational, evidence-minded way.

Fast snapshot

• Fewer men are counted as "in the labor force" (employed or actively looking) than at almost any point since the U.S. Bureau of Labor Statistics began tracking this in 1948.
• The declines are concentrated among younger men (teens to 30s) and older men (late 50s and up).
• The causes are multiple: health and disability, shifting family roles, skills and job mismatch, incarceration and legal barriers, retirement choices, and long-run changes in demand for certain kinds of labor.

Why the headline matters

This isn’t just an accounting curiosity. Labor force participation affects wages, tax revenue, social stability, and how we think about opportunity. When men drop out of work, families lose income; employers scramble to find labor; and policymakers face hard choices about training, benefits, and social supports.

Transitioning to the evidence: the data show clear long-term trends and recent accelerations. Federal series from the BLS and compilations on FRED and other data sites document the decline in the male participation rate that the Washington Post reported. Complementary analyses from think tanks and labor economists help explain what’s behind the numbers. (Sources at the end.)

The pieces of the puzzle

• Health, disability, and mental health

  • Disability rates among working-age men have risen in some groups, and opioid- and mental-health-related problems discourage or prevent steady work. Long-term health shocks can push men out of the labor force permanently.

• Education and skills mismatch

  • The modern economy increasingly rewards higher education and cognitive/technical skills. Men without those credentials see fewer good opportunities in manufacturing and routine middle-skill jobs that have been automated or offshored.

• Criminal records and re-entry barriers

  • A significant share of prime-age men who are not working have criminal records. Legal barriers and employer screening can shut large numbers out of the formal labor market.

• Family, caregiving, and social norms

  • Younger men sometimes opt out temporarily to pursue education, caregiving, or nontraditional work paths. For some, the calculation of costs (childcare, housing, transportation) versus wages makes work less attractive.

• Retirement and delayed retirement patterns among older men

  • Some older men who might previously have retired later are now leaving the workforce earlier for health or family reasons — while others stay longer, creating a complicated age mix.

• Labor demand and macro conditions

  • Softer job openings, shifting industry composition, and technology that replaces routine tasks all reduce opportunities for certain male-dominated occupations.

These factors interact. A factory closure combines with an injury, a criminal record, or low local opportunity and the outcome is often permanent detachment from work.

The numbers that sting

Look at the long-run series: male labor force participation has been trending down for decades. The broad participation rate for men today is at a level not seen since the late 1940s, except during the pandemic slump. That’s not just a blip; it’s the result of cumulative changes in sectors, policy, and demographics. (See sources below for the BLS/FRED historical series and recent analyses.)

Who’s most affected

• Young men without college credentials: they face the steepest odds of non-participation, particularly in areas hit by industrial decline or with limited service-sector alternatives.
• Older men with health problems or marginal attachment to the labor market: a health shock or caregiving need can push them out for good.
• Men with criminal justice involvement: barriers to employment after incarceration remain a major structural problem.

Why policy debates are hard

There’s no single fix. Policies that help one group can miss another. Consider these trade-offs:

• Expand training and credentialing programs: helpful for many, but slow and expensive.
• Improve healthcare and disability support: necessary for humane outcomes, but can reduce incentives to return to work unless paired with re-entry supports.
• Remove legal barriers for hiring people with records: promising, but politically contentious.
• Boost demand via fiscal policy or job guarantees: effective but costly and often politically divisive.

A smart approach mixes prevention (education, addiction services, mental health), removal of unnecessary barriers (licensing reform, reentry supports), and demand-side measures where needed.

A few surprising nuances

• The decline is not uniform across places. States and metro areas with strong service economies or tech hubs often show different patterns than rural, manufacturing-dependent areas.
• Women’s participation trends have their own story, and gendered labor shifts interact. In some households, the woman’s work status influences the man’s decision to participate.
• Some “drops” represent voluntary choices (education, entrepreneurship, caregiving), not just failure to find work. Distinguishing between voluntary and involuntary nonparticipation matters for policy.

What employers and communities can do

• Invest in local hiring pipelines and on-the-job training that don’t require lengthy credentials.
• Partner with reentry programs and reduce unnecessary licensing that bars hiring.
• Offer flexible schedules and support services (childcare, mental-health access) that help keep or bring people back into work.

A reality check

These trends reflect deep structural changes. We shouldn’t expect quick reversals. But targeted policy and local action can blunt the harm and help reattach many men to stable employment.

My take

This moment is an invitation to re-think how we value and structure work. If the economy is leaving some men behind because jobs have changed, then our social and policy responses must change too — not with quick fixes, but with a realistic combination of health supports, fair hiring practices, training tied to real opportunities, and community-based solutions. That’s how we rebuild durable pathways back into the labor market.

Sources

• Labor Force Participation Rate – Men (FRED, St. Louis Fed).
  https://fred.stlouisfed.org/data/LNU01300001

• Labor force participation and historical context (USAFacts).
  https://usafacts.org/articles/labor-force-participation-rate-and-the-pandemic/

• Good news and bad news about U.S. labor force participation (Economic Policy Institute).
  https://www.epi.org/publication/good-news-and-bad-news-about-u-s-labor-force-participation-many-headwinds-from-the-2010s-are-gone-but-were-not-investing-enough-in-the-future/

• Why young and old men are leaving the labor force at record rates (The Washington Post).
  https://www.washingtonpost.com/business/ (search the WaPo title for the full article)

• Where Have All the Workers Gone? An Inquiry into the Decline of the U.S. Labor Force Participation Rate (National Institutes of Health / PMC).
  https://pmc.ncbi.nlm.nih.gov/articles/PMC6364990/